Was Angelina Jolie Right? Optimizing Cancer Prevention Strategies Among BRCA Mutation Carriers
Published Online:12 Jul 2017https://doi.org/10.1287/deca.2017.0352
References
- (2015) A MDP model for breast and ovarian cancer intervention strategies for BRCA1/2 mutation carriers. IEEE J. Biomedical Health Informatics 19(2):720–727.Crossref, Google Scholar
- (2013) Optimal policies for reducing unnecessary follow-up mammography exams in breast cancer diagnosis. Decision Anal. 10(3):200–224.Link, Google Scholar
- (2010) Markov decision processes: A tool for sequential decision making under uncertainty. Medical Decision Making 30(4):474–483.Crossref, Google Scholar
- (2004) The optimal timing of living-donor liver transplantation. Management Sci. 50(10):1420–1430.Link, Google Scholar
- (2006) Cost-effectiveness of preventive strategies for women with a BRCA1 or a BRCA2 mutation. Ann. Internal Medicine 144(6):397–406.Crossref, Google Scholar
- (2003) Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: A combined analysis of 22 studies. Amer. J. Human Genetics 72(5):1117–1130.Crossref, Google Scholar
- (2004) Hormone replacement therapy and life expectancy after prophylactic oophorectomy in women with BRCA1/2 mutations: A decision analysis. J. Clinical Oncology 22(6):1045–1054.Crossref, Google Scholar
- (2012) Trajectories of health-related quality of life differ by age among adults: Results from an eight-year longitudinal study. J. Health Econom. 31(1):207–218.Crossref, Google Scholar
- (2012) OR Forum—A POMDP approach to personalize mammography screening decisions. Oper. Res. 60(5):1019–1034.Link, Google Scholar
- (1965) Mathematical Theory of Reliability (John Wiley & Sons, New York).Google Scholar
- (2005) Complications following bilateral prophylactic mastectomy. JNCI Monographs 2005(35):61–66.Crossref, Google Scholar
- (2012) Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer. J. Amer. Medical Assoc. 307(4):382.Crossref, Google Scholar
- Breastcancer.org (2017) U.S. breast cancer statistics. Accessed June 15, 2017, http://www.breastcancer.org/symptoms/understand_bc/statistics.Google Scholar
- (2008) The role of human epidermal growth factor receptor 2 in the survival of women with estrogen and progesterone receptor-negative, invasive breast cancer: The California Cancer Registry, 1999–2004. Cancer 112(4):737–747.Crossref, Google Scholar
- Centers for Disease Control and Prevention (CDC) (2014) Underlying cause of death 1999–2015. CDC WONDER online database, released 2015. Accessed June 15, 2017, http://wonder.cdc.gov/ucd-icd10.html.Google Scholar
- (2007) Meta-analysis of BRCA1 and BRCA2 penetrance. J. Clinical Oncology 25(11):1329–1333.Crossref, Google Scholar
- (2010) Optimal breast biopsy decision-making based on mammographic features and demographic factors. Oper. Res. 58(6):1577–1591.Link, Google Scholar
- (2003) The linear programming approach to approximate dynamic programming. Oper. Res. 51(6):850–865.Link, Google Scholar
- (2006) Mortality after bilateral salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers: A prospective cohort study. Lancet Oncology 7(3):223–229.Crossref, Google Scholar
- (2010) Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality. J. Amer. Medical Assoc. 304(9):967–975.Crossref, Google Scholar
- (2002) Estimates of the likely prophylactic effect of tamoxifen in women with high risk BRCA1 and BRCA2 mutations. British J. Cancer 86(2):218–221.Crossref, Google Scholar
- (2010) The American Joint Committee on Cancer: The 7th edition of the AJCC cancer staging manual and the future of TNM. Ann. Surgical Oncology 17(6):1471–1474.Crossref, Google Scholar
- (2005) Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: An international case-control study. J. Clinical Oncology 23(30):7491–7496.Crossref, Google Scholar
- (2015) Longer term effects of the Angelina Jolie effect: Increased risk-reducing mastectomy rates in BRCA carriers and other high-risk women. Breast Cancer Res. 17:143.Crossref, Google Scholar
- (2014) The Angelina Jolie effect: How high celebrity profile can have a major impact on provision of cancer related services. Breast Cancer Res. 16:442.Crossref, Google Scholar
- (2001) Prophylactic oophorectomy versus screening: Psychosocial outcomes in women at increased risk of ovarian cancer. Psycho-Oncology 10(3):231–241.Crossref, Google Scholar
- (2014) Risk management options elected by women after testing positive for a BRCA mutation. Gynecologic Oncology 132(2):428–433.Crossref, Google Scholar
- (1983) Decision-aiding models: Validation, assessment, and related issues for policy analysis. Oper. Res. 31(4):603–631.Link, Google Scholar
- (2006) Contentment with quality of life among breast cancer survivors with and without contralateral prophylactic mastectomy. J. Clinical Oncology 24(9):1350–1356.Crossref, Google Scholar
- (2009) Contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers. J. Clinical Oncology 27(35):5887–5892.Crossref, Google Scholar
- (1998) Decision analysis of prophylactic mastectomy and oophorectomy in BRCA1-positive or BRCA2-positive patients. J. Clinical Oncology 16(3):979–985.Crossref, Google Scholar
- (1999a) The quality of life associated with prophylactic treatments for women with BRCA1/2 mutations. Cancer J. Sci. Amer. 5(5):283–292.Google Scholar
- (2002) Effect of prevention strategies on survival and quality-adjusted survival of women with BRCA1/2 mutations: An updated decision analysis. J. Clinical Oncology 20(10):2520–2529.Crossref, Google Scholar
- (1999b) Benefits and costs of screening Ashkenazi Jewish women for BRCA1 and BRCA2. J. Clinical Oncology 17(2):494–500.Crossref, Google Scholar
- (2010) Breast cancer-related preferences among women with and without BRCA mutations. Breast Cancer Res. Treatment 119(1):177–184.Crossref, Google Scholar
- (2014) Converting an odds ratio to a range of plausible relative risks for better communication of research findings. British Medical J. 348(January):1–7.Google Scholar
- (1990) Linkage of early-onset familial breast cancer to chromosome 17q21. Science 250(4988):1684–1689.Crossref, Google Scholar
- (2009) BRCA1 and BRCA2 mutations in women of different ethnicities undergoing testing for hereditary breast–ovarian cancer. Cancer 115(10):2222–2233.Crossref, Google Scholar
- (2015) How medical choices influence quality of life of women carrying a BRCA mutation. Critical Rev. Oncology/Hematology 96(3):555–568.Crossref, Google Scholar
- (2001) Efficacy of bilateral prophylactic mastectomy in BRCA1 and BRCA2 gene mutation carriers. J. Natl. Cancer Inst. 93(21):1633–1637.Crossref, Google Scholar
- (2017) Patient education: Treatment of metastatic breast cancer (beyond the basics). Accessed June 15, 2017, http://www.uptodate.com/contents/treatment-of-metastatic-breast-cancer-beyond-the-basics.Google Scholar
- (2007) Prevalence of pathogenic BRCA1 mutation carriers in 5 US racial/ethnic groups. J. Amer. Medical Assoc. 298(24):2869–2876.Crossref, Google Scholar
- (2013) My medical choice. New York Times (May 14), http://www.nytimes.com/2013/05/14/opinion/my-medical-choice.html.Google Scholar
- (2015) Diary of a surgery. New York Times (March 24), https://www.nytimes.com/2015/03/24/opinion/angelina-jolie-pitt-diary-of-a-surgery.html.Google Scholar
- (2013) A comprehensive focus on global spectrum of BRCA1 and BRCA2 mutations in breast cancer. BioMed Res. Internat. 2013:928562.Crossref, Google Scholar
- (2008) Risk-reducing salpingo-oophorectomy for the prevention of BRCA1- and BRCA2-associated breast and gynecologic cancer: A multicenter, prospective study. J. Clinical Oncology 26(8):1331–1337.Crossref, Google Scholar
- (2001) Tamoxifen and breast cancer incidence among women with inherited mutations in BRCA1 and BRCA2: National Surgical Adjuvant Breast and Bowel Project (NSABP-P1) Breast Cancer Prevention Trial. J. Amer. Medical Assoc. 286(18):2251–2256.Crossref, Google Scholar
- (2010) Survival analysis of cancer risk reduction strategies for BRCA1/2 mutation carriers. J. Clinical Oncology 28(2):222–231.Crossref, Google Scholar
- (2014) Use of and mortality after bilateral mastectomy compared with other surgical treatments for breast cancer in California, 1998–2011. J. Amer. Medical Assoc. 312(9):902–914.Crossref, Google Scholar
- (2012) Online tool to guide decisions for BRCA1/2 mutation carriers. J. Clinical Oncology 30(5):497–506.Crossref, Google Scholar
- (2003) Ovarian cancer in elderly women. Oncology 17(8):1075–1081.Google Scholar
- (2011) Clinical outcome of triple negative breast cancer in BRCA1 mutation carriers and noncarriers. Cancer 117(14):3093–3100.Crossref, Google Scholar
- (2015) Prognosis of metastatic breast cancer: Are there differences between patients with de novo and recurrent metastatic breast cancer? British J. Cancer 112(9):1445–1451.Crossref, Google Scholar
- (2015) Cost-effectiveness of universal BRCA1/2 screening: Evidence-based decision making. JAMA Oncology 1(9):1217–1218.Crossref, Google Scholar
- (2005) Quality-of-life effects of prophylactic salpingo-oophorectomy versus gynecologic screening among women at increased risk of hereditary ovarian cancer. J. Clinical Oncology 23(28):6890–6898.Crossref, Google Scholar
- (2012) Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: Results from the consortium of investigators of modifiers of BRCA1/2 (CIMBA). Cancer Epidemiology, Biomarkers Prevention 21(1):134–147.Crossref, Google Scholar
- (2001) Efficacy of contralateral prophylactic mastectomy in women with a personal and family history of breast cancer. J. Clinical Oncology 19(19):3938–3943.Crossref, Google Scholar
- (2005) The risk of ovarian cancer after breast cancer in BRCA1 and BRCA2 carriers. Gynecologic Oncology 96(1):222–226.Crossref, Google Scholar
- (2009) Fatigue and quality of life after risk-reducing salpingo-oophorectomy in women at increased risk for hereditary breast-ovarian cancer. Internat. J. Gynecological Cancer 19(6):1029–1036.Crossref, Google Scholar
- (2004) Endogenous estrogen, androgen, and progesterone concentrations and breast cancer risk among postmenopausal women. J. Natl. Cancer Inst. 96(24):1856–1865.Crossref, Google Scholar
- National Comprehensive Cancer Network (2016) NCCN clinical practice guidelines in oncology. Genetic/familial assessment: Breast and ovarian. Accessed June 15, 2017, https://www.nccn.org/professionals/physician_gls/pdf/genetics_screening.pdf.Google Scholar
- (2014) High risk of in-breast tumor recurrence after BRCA1/2-associated breast cancer. Breast Cancer Res. Treatment 147(3):571–578.Crossref, Google Scholar
- (2014) Breast cancer survival defined by the ER/PR/HER2 subtypes and a surrogate classification according to tumor grade and immunohistochemical biomarkers. J. Cancer Epidemiology 2014(2):469251.Google Scholar
- (2011) Approximate Dynamic Programming: Solving the Curses of Dimensionality, 2nd ed. (John Wiley & Sons, Hoboken, NJ).Crossref, Google Scholar
- (2014) Markov Decision Processes: Discrete Stochastic Dynamic Programming (John Wiley & Sons, Hoboken, NJ).Google Scholar
- (2009) Meta-analysis of risk reduction estimates associated with risk-reducing salpingo-oophorectomy in BRCA1 or BRCA2 mutation carriers. J. Natl. Cancer Inst. 101(2):80–87.Crossref, Google Scholar
- (2004) Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: The PROSE Study Group. J. Clinical Oncology 22(6):1055–1062.Crossref, Google Scholar
- (2003) A combined analysis of outcome following breast cancer: Differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment. Breast Cancer Res. 6(1):14680495.Crossref, Google Scholar
- (2010) Risk-reducing strategies for women carrying BRCA1/2 mutations with a focus on prophylactic surgery. BMC Women’s Health 10:28.Crossref, Google Scholar
- (2013) Verification and validation of simulation models. J. Simulation 7(1):12–24.Crossref, Google Scholar
- (2000) Life expectancy gains from cancer prevention strategies for women with breast cancer and BRCA1 or BRCA2 mutations. J. Amer. Medical Assoc. 283(5):617–624.Crossref, Google Scholar
- (1997) Decision analysis—Effects of prophylactic mastectomy and oophorectomy on life expectancy among women with BRCA1 or BRCA2 mutations. New England J. Medicine 336(20):1465–1471.Crossref, Google Scholar
- (2008) Prophylactic oophorectomy in premenopausal women and long-term health. Menopause Internat. 14(3):111–116.Crossref, Google Scholar
- (2003) Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc. Natl. Acad. Sci. USA 100(14):8418–8423.Crossref, Google Scholar
- (2000) One thousand health-related quality-of-life estimates. Medical Care 38(6):583–637.Crossref, Google Scholar
- (2007) Quality of life after contralateral prophylactic mastectomy in newly diagnosed high-risk breast cancer patients who underwent BRCA1/2 gene testing. J. Clinical Oncology 25(3):285–291.Crossref, Google Scholar
- (1995) A prospective study of endogenous estrogens and breast cancer in postmenopausal women. J. Natl. Cancer Inst. 87(3):190–197.Crossref, Google Scholar
- (2010) The role of BRCA mutation testing in determining breast cancer therapy. Nature Rev. Clinical Oncology 7(12):708–717.Crossref, Google Scholar
- (2011) HE4 and CA125 as a diagnostic test in ovarian cancer: Prospective validation of the Risk of Ovarian Malignancy Algorithm. British J. Cancer 104(5):863–870.Crossref, Google Scholar
- (2002) Decision analysis of prophylactic surgery or screening for BRCA1 mutation carriers: A more prominent role for oophorectomy. J. Clinical Oncology 20(8):2092–2100.Crossref, Google Scholar
- (1989) Markov decision processes. Eur. J. Oper. Res. 39(1):1–16.Crossref, Google Scholar
- (1994) Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13. Science 265(5181):2088–2090.Crossref, Google Scholar
- World Cancer Research Fund International (2015) Cancer facts and figures—Worldwide data. Accessed June 15, 2017, http://www.wcrf.org/int/cancer-facts-figures/worldwide-data.Google Scholar

